瞭望前瞻丨SABCS 2025盛幕将启,中国之声亮相世界舞台(Poster Session 3精选)

作者:肿瘤瞭望   日期:2025/12/8 13:40:41  浏览量:205

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第48届圣安东尼奥乳腺癌研讨会(SABCS 2025)将于当地时间2025年12月9-12日在美国得克萨斯州圣安东尼奥Henry B.Gonzalez Convention Center举行。作为乳腺癌领域的顶级盛会,SABCS聚焦乳腺癌生物学、病因、预防、诊断及治疗前沿,促进临床、转化与基础研究的深度融合,为全球科研人员提供交流协作与专业成长的平台。肿瘤瞭望-乳腺时讯特别对Rapid Fire、Poster Spotlight、Poster Session等环节中国专家的报告内容进行汇总,以便读者快速了解会议动态。本文将介绍Poster Session 3环节入选中国研究,敬请关注后续详细报道!(注:如有遗漏或错误,欢迎留言指正。)

编者按:第48届圣安东尼奥乳腺癌研讨会(SABCS 2025)将于当地时间2025年12月9-12日在美国得克萨斯州圣安东尼奥Henry B.Gonzalez Convention Center举行。作为乳腺癌领域的顶级盛会,SABCS聚焦乳腺癌生物学、病因、预防、诊断及治疗前沿,促进临床、转化与基础研究的深度融合,为全球科研人员提供交流协作与专业成长的平台。肿瘤瞭望-乳腺时讯特别对Rapid Fire、Poster Spotlight、Poster Session等环节中国专家的报告内容进行汇总,以便读者快速了解会议动态。本文将介绍Poster Session 3环节入选中国研究,敬请关注后续详细报道!(注:如有遗漏或错误,欢迎留言指正。)
 
Poster Session 3
时间:12月11日12:30 PM–2:00 PM CST
地点:Exhibit Hall
 
摘要号:PS3-01-16
Gut microbial dysbiosis associates with the early-onset breast cancer in BRCA mutation carriers
肠道微生物失调与BRCA突变携带者的早发性乳腺癌相关
讲者:Po-Han Lin(台湾大学医学院)
 
摘要号:PS3-02-02
Impact of COVID-19 on neoadjuvant chemotherapy efficacy in patients with breast cancer:an ambidirectional cohort study and Mendelian randomization analysis
COVID-19对乳腺癌患者新辅助化疗疗效的影响:一项双向队列研究和孟德尔随机化分析
讲者:Yali Wang(福建医科大学附属协和医院)
 
摘要号:PS3-02-05
Shared Genetic Architecture between Breast Cancer and Psychiatric Disorders:Insights from Large-Scale Genome-wide Cross-trait Analysis
乳腺癌和精神疾病之间的共享遗传架构:来自大规模全基因组交叉性状分析的见解
讲者:Canzhou Wang(山西医科大学第一医院)
 
摘要号:PS3-03-09
Charting the shared genetic architecture between breast cancer and major depressive disorder based on genome-wide association study
基于全基因组关联研究绘制乳腺癌和重性抑郁障碍之间的共享遗传结构
讲者:Yilong Lin(厦门大学附属第一医院)
 
摘要号:PS3-03-10
Whole exome sequencing reveals germline pathogenic variant landscape in multi-center Taiwanese breast cancer patient cohort at moderate to high hereditary genetic risks
全外显子组测序揭示中高危遗传性风险的多中心中国台湾乳腺癌患者队列的生殖系致病性变异图谱
讲者:Wen-Ling Kuo(桃园长庚纪念医院)
 
摘要号:PS3-03-14
Knowledge,Attitude and Practice of Gynecological Oncologists on Breast Cancer-related Risks in BRCA1/2 Germline Mutation-related Ovarian Cancer Patients
妇科肿瘤医师对BRCA1/2生殖细胞系突变相关卵巢癌患者乳腺癌相关风险的知识、态度和行为
讲者:Fengxia Gan(中山大学孙逸仙纪念医院)
 
摘要号:PS3-03-27
Potential genetic targets of recurrence at different time points in Asia breast cancer with NanoString and multigene prognostic test
通过纳米弦技术及多基因预后检测,探索亚洲乳腺癌不同时间点复发的潜在遗传靶点
讲者:Ming Feng Hou(高雄医科大学附属医院)
 
摘要号:PS3-05-06
Landscape of PIK3CA Mutations in Chinese Patients with Breast Cancer:A Multi-Center Real-World Study
中国乳腺癌患者的PIK3CA突变情况:一项多中心真实世界研究
讲者:徐菲(中山大学肿瘤防治中心)
 
摘要号:PS3-05-14
Clinical significance of pathogenic variants in breast cancer patients at risk for hereditary breast cancer
致病变异体在有遗传性乳腺癌风险的乳腺癌患者中的临床意义
讲者:Xiaying Kuang(中山大学附属第一医院)
 
摘要号:PS3-05-21
Pathogenic germline variants associated with different HER2 expression among breast cancer patients
乳腺癌患者中与不同HER2表达相关的致病性生殖细胞系变异体
讲者:廖宁(广东省人民医院)
 
摘要号:PS3-04-02
A Novel Non-invasive Machine Learning Model for Predicting Tertiary Lymphoid Structures and Treatment Response to Neoadjuvant Therapy in Triple-Negative Breast Cancer:A Multicenter Retrospective Study
用于预测三阴性乳腺癌新辅助治疗后三级淋巴结构和治疗反应的新型无创机器学习模型:一项多中心回顾性研究
讲者:Yidan Lin(福建省肿瘤医院)
 
摘要号:PS3-06-09
Her2-ladder:a spatially interpretable artificial intelligence-driven model for tailored dual-targeted therapy in HER2-positive breast cancer
Her2-ladder:一种空间可解释的人工智能驱动模型,用于HER2阳性乳腺癌的个体化双靶向治疗
讲者:Xiang-Rong Wu(复旦大学附属肿瘤医院)
 
摘要号:PS3-06-13
Early Prediction of Pathologic Complete Response in Breast Cancer via Graph Network Modeling of Intratumoral and Peritumoral Dynamics on DCE-MRI
通过动态对比增强磁共振(DCE-MRI)上肿瘤内及肿瘤周围动态变化的图网络建模,实现乳腺癌病理完全缓解的早期预测
讲者:Yuyi Tan(中国科学院自动化研究所)
 
摘要号:PS3-06-16
Mapping neutrophil architecture with integrative spatial analysis to reveal clinically relevant functional heterogeneity
通过整合空间分析绘制中性粒细胞结构以揭示临床相关的功能异质性
讲者:Yu-Zheng Xu(复旦大学附属肿瘤医院)
 
摘要号:PS3-06-20
A rapid and accurate diagnostic system based on label-free multimodal multiphoton microscopy and deep learning
基于非标记多模态多光子显微镜和深度学习的快速准确诊断系统
讲者:Yulei Wang(广东省人民医院)
 
摘要号:PS3-07-02
An Exploratory Clinical Trial of CDK4/6 Inhibitor Dalpiciclib Combined with Aromatase Inhibitors as Neoadjuvant Therapy for Stage II-III HR-positive HER2-negative Breast Cancer
CDK4/6抑制剂达尔西利联合芳香化酶抑制剂作为HR+/HER2-II-III期乳腺癌新辅助治疗的探索性临床试验
讲者:杨清默(厦门大学附属第一医院)
 
摘要号:PS3-07-04
Neoadjuvant chemotherapy combined with Toripalimab for HR+/HER2-breast cancer:a prospective,single-arm,multi-center clinical study(NEOTORCH-BREAST01)
新辅助化疗联合特瑞普利单抗治疗HR+/HER2-乳腺癌的前瞻性、单臂、多中心临床研究(NEOTORCH-BREAST01)
讲者:Zhijun Dai(浙江大学医学院附属第一医院)
 
摘要号:PS3-07-25
Clinical Characteristics of Chinese Patients with Early Invasive Breast Cancer Tested with 70-gene signature:Comparison with the MINDACT Cohort
使用70基因检测的中国早期浸润性乳腺癌患者临床特征:与MINDACT队列的比较
讲者:刘红(天津医学大学肿瘤医院)
 
摘要号:PS3-07-26
Precision neoadjuvant treatment with Artificial Intelligence assisted subtyping in HR+/HER2-breast cancer:a randomized,open-label,phase 2 trial FASCINATE-N
人工智能辅助分型精准新辅助治疗HR+/HER2-乳腺癌:一项随机、开放标签、2期试验FASCINATE-N
讲者:李俊杰(复旦大学附属肿瘤医院)
 
摘要号:PS3-08-04
Dalpiciclib Combined with Letrozole as Neoadjuvant Therapy for Stage II-III HR-Positive,HER2-Negative Breast Cancer:A Phase II Study
达尔西利联合来曲唑作为II-III期HR+/HER2-乳腺癌的新辅助治疗:一项II期研究
讲者:Yan Mao(青岛大学附属医院)
 
摘要号:PS3-10-01
Impact of ER Reduction Rate on Survival Outcomes in ER-Positive/HER2-Negative Breast Cancer Post-Neoadjuvant Chemotherapy
ER减低率对ER+/HER2-乳腺癌新辅助化疗后生存结局的影响
讲者:Shunyi Liu(福建医科大学附属协和医院)
 
摘要号:PS3-10-06
Comparison between the LRP model and Adjuvant!Online in predicting 9-year distant disease-free survival
LRP模型与Adjuvant!Online在预测9年无远处转移生存率方面的比较
讲者:徐玲(北京大学肿瘤医院)
 
摘要号:PS3-10-15
Smarcd3 co-suppresses erαsignaling pathway mediates tumor progression and its role in anti-estrogen resistance in breast cancer
Smarcd3共抑制erα信号通路介导的肿瘤进展及其在乳腺癌抗雌激素抵抗中的作用
讲者:Haoran Dong(中国医科大学附属第一医院)
 
摘要号:PS3-10-22
An Online Tool to Assist Decisions on Chemotherapy for Men with Luminal Early Breast Cancer
辅助Luminal型早期乳腺癌男性患者化疗决策的在线工具
讲者:Yuxuan Gao(中山大学附属第一医院)
 
摘要号:PS3-10-29
Ner-tree study interim analysis of safety and patient-reported outcomes in patients with human epidermal growth factor receptor 2 positive(HER2+)early breast cancer(eBC)treated with neratinib in China
Ner-tree研究中期分析:中国接受奈拉替尼治疗的HER2+早期乳腺癌(eBC)患者的安全性和患者报告结局
讲者:王晓稼(浙江省肿瘤医院)
 
摘要号:PS3-11-05
Trastuzumab Combined with Pyrotinib and Capecitabine as Postoperative Adjuvant Therapy in Non-Pathological Complete Response HER2-Positive Early Breast Cancer Following Neoadjuvant Therapy:A Multicenter Phase II Study
曲妥珠单抗联合吡咯替尼和卡培他滨作为新辅助治疗后非病理完全缓解的HER2阳性早期乳腺癌的术后辅助治疗:一项多中心II期研究
讲者:Jie Zhang(福建医科大学附属协和医院)
 
摘要号:PS3-11-08
Subcutaneous pertuzumab and trastuzumab fixed-dose combination versus dual intravenous pertuzumab and trastuzumab or subcutaneous trastuzumab plus intravenous pertuzumab in HER2-positive breast cancer adjuvant therapy:A time and motion study in a lean operating day care oncology unit in China
固定剂量曲帕双靶皮下制剂联合治疗与曲帕双靶静脉注射方案或曲妥珠单抗皮下注射+帕妥珠单抗静脉注射方案在HER2阳性乳腺癌辅助治疗中的对比:一项在中国肿瘤科日间手术病房进行的时间和运动研究
讲者:Amei Huang(山东第一医科大学肿瘤医院)
 
摘要号:PS3-11-12
Efficacy and safety of disitamab vedotin combined with pyrotinib as neoadjuvant therapy for HER2-positive breast cancer:a phase II trial
维迪西妥单抗联合吡咯替尼作为HER2阳性乳腺癌新辅助治疗的疗效与安全性:一项Ⅱ期临床试验
讲者:Tianyu Zeng(江苏省人民医院)
 
摘要号:PS3-11-15
Comprehensive Analysis and Prediction of HER2-targeted Therapy Insensitivity among HER2-Positive Breast Cancer Patients Undergoing Neoadjuvant treatment
接受新辅助治疗的HER2阳性乳腺癌患者HER2靶向治疗不敏感的综合分析和预测
讲者:Qingyao Shang(中国医学科学院肿瘤医院)
 
摘要号:PS3-11-22
Efficacy and safety of 12-week adjuvant docetaxel plus trastuzumab in patients with node-negative HER2-positive breast cancer(tumors≤1cm):results from the SOBER prospective single-arm trial
12周多西他赛联合曲妥珠单抗辅助治疗对淋巴结阴性HER2阳性乳腺癌(肿瘤≤1cm)患者的疗效和安全性:来自SOBER前瞻性单组试验的结果
讲者:Shuning Ding(上海交通大学医学院附属第一人民医院)
 
摘要号:PS3-11-26
A real-world study of pyrotinib as neoadjuvant therapy for HER2-positive breast cancer
吡咯替尼作为HER2阳性乳腺癌新辅助治疗的真实世界研究
讲者:郑红梅(湖北省肿瘤医院)
 
摘要号:PS3-11-30
Neoadjuvant pyrotinib,trastuzumab,dalpiciclib,and exemestane in triple-positive breast cancer:a multicenter phase II trial
新辅助吡咯替尼、曲妥珠单抗、达尔西利联合依西美坦治疗三阳性乳腺癌:一项多中心II期试验
讲者:傅佩芬(浙江大学医学院附属第一医院)
 
摘要号:PS3-12-17
Baicalein Reverses CAFs Activation in Triple-Negative Breast Cancer by Inhibiting the PI3K/Akt/mTOR Pathway
黄芩素通过抑制PI3K/Akt/mTOR通路逆转三阴性乳腺癌中CAFs的激活
讲者:Wei Lv(西安交通大学第二附属医院)
 
摘要号:PS3-12-25
First Preclinical Evaluation of Inavolisib-Based Combinatorial Strategies in PIK3CA-Mutant Breast Cancer Brain Metastasis Models
基于伊那利塞的组合策略在PIK3CA突变乳腺癌脑转移模型中的首次临床前评估
讲者:赵健丽(中山大学孙逸仙纪念医院)
 
摘要号:PS3-13-01
Cik cell therapy remodels the immune microenvironment and suppresses cutaneous metastatic breast cancer in preclinical models
在临床前模型中,Cik细胞治疗重塑免疫微环境并抑制皮肤转移性乳腺癌
讲者:Chi-Wen Luo(高雄医科大学附属医院)
 
摘要号:PS3-02-18
Association of epidemiological and reproductive factors with risk of hormone receptor-positive/negative breast cancer:a case-control study in Beijing,China(CABC011)
流行病学和生殖因素与激素受体阳性/阴性乳腺癌关联的病例对照研究(CABC011)
讲者:李惠平(北京大学肿瘤医院)
 
摘要号:PS3-05-28
Landscape of homologous recombination repair-related gene mutation and homologous recombination deficiency in Chinese patients with HER2-low early breast cancer
中国HER2低表达早期乳腺癌患者的同源重组修复相关基因突变和同源重组缺陷情况
讲者:龚畅(中山大学孙逸仙纪念医院)
 
摘要号:PS3-06-14
Interpretable Graph Learning on Preoperative Biopsy Predicts Pathological Complete Response to Neoadjuvant Therapy in Breast Cancer
术前活检的可解读图学习预测乳腺癌新辅助治疗后的病理完全缓解
讲者:张国君(云南省肿瘤医院)
 
摘要号:PS3-06-15
A Retrospective Study on a Predictive Model to Probe the Impact of Atmospheric Environment on Breast Cancer Prognosis:A Cohort of 17,438 Patients
探讨大气环境对乳腺癌预后影响的预测模型的回顾性研究:包含17438例患者的队列
讲者:Yunqin Yuan(台州学院人工智能学院)

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